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Broccoli Compound Destroys Cancer Cells

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BroccoliResearch published in the journal, Molecular Nutrition & Food Research, explains the potent mechanism exhibited by cruciferous vegetables such as broccoli and cauliflower to ameliorate developing cancer cells. The active photochemical known as sulforaphane targets prostate and other hormone dependent cancer lines and leaves normal healthy cells unaffected.

Cruciferous vegetables have long been associated with a lowered risk of prostate cancer, but this is the first study to demonstrate the “search and attack” capability of the natural chemical compound. Consuming small amounts of crucifers several times each week can help to significantly lower your risk of developing many types of potentially deadly cancer lines.

Sulforaphane from Crucifers Shown to Target Cancer Cells for Destruction

The study was led by Dr. Emily Ho, associate professor from the Linus Pauling Institute at Oregon State University. Tissue from cruciferous vegetables such as broccoli, cabbage and cauliflower contain high levels of the powerful natural compound chemically known as glucosinolates. In the body glucosinolates are broken down into sulforaphane that exert protective anti-cancer characteristics.

Based on prior research to indicate that crucifers and sulforaphane specifically kill cancer cells, researchers designed a trial study using mouse models to demonstrate that sulforaphane selectively targets hormone dependent cancers such as breast and prostate. Dr. Ho commented “It is well documented that sulforaphane can target cancer cells through multiple chemopreventive mechanisms” and  continued, “Here we show for the first time that sulforaphane selectively targets benign hyperplasia cells and cancerous prostate cells while leaving the normal prostate cells unaffected.”

Broccoli Compound Inhibits Enzymes that Drive Cancer Growth

The study demonstrated that sulforaphane is an inhibitor of histone deacetylase, or HDAC enzymes. HDAC enzymes are theorized to develop in the body as a result of metabolic inefficiency resulting from systemic inflammation and low antioxidant status. HDAC enzymes provide fuel to the cancer initiation and progression processes when they occur in excess and their action runs unabated. HDAC inhibition is currently an important research area targeted by Big Pharma and synthesized drugs that can be addressed with natural nutrients from food and lifestyle modifications.

Scientists clearly demonstrated the specific mechanism to explain how sulforaphane targets breast and prostate cancer cells. Many existing studies show that nutrients present in cruciferous vegetables can halt all cancer cell lines by inhibiting the fuel necessary for the cells to multiply out of control. Researchers concluded the data collected “provide(s) further support for the relevance of sulforaphane as a dietary HDAC inhibitor and chemopreventive agent.” Nutritional experts recommend several three to four ounce servings of lightly steamed crucifers each week to prevent cancer development.

References:

http://www.sciencedaily.com/releases/2011/06/110609123334.htm
http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201000547/abstract;jsessionid=794267A1F332ABF8D0A51DAF1BEB2556.d01t04
http://lefcms.lef.org/newsletter/2011/0614_Broccoli-Compound-Goes-After-Cancer-Cells.htm
http://www.nutraingredients.com/Research/Broccoli-extract-can-target-cancer-cells-Study/

 


 

John Phillip is a diet, health and nutrition researcher and writer with a passion for understanding weight loss challenges and encouraging health modification through natural diet, lifestyle and targeted supplementation. John’s passion is to research and write about the cutting edge alternative health technologies that affect our lives.

Discover the latest alternative health news concerning diabetes, heart disease, cancer, dementia and weight loss at My Optimal Health Resource.

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4 responses to “Broccoli Compound Destroys Cancer Cells”

  1. […] known to boost DNA repair and inhibit cancer cell growth, as well as sulforaphane, a chemical believed to have anti-cancer properties. Unfortunately, the most common preparations, boiling or steaming, rob these mini-cabbages of […]

  2. […] Not only are Brussels sprouts are an excellent source of vitamin C, they also contain indole-3-carbinol, a compound known to boost DNA repair and inhibit cancer cell growth, as well as sulforaphane, a chemical believed to have anti-cancer properties. […]

  3. […] treatment is dealing with fears of a reoccurrence. New research indicates the consumption of certain vegetables may be proactive in lowering the risk of a relapse. In a study involving Chinese women diagnosed […]

  4. […] have been mounting evidence to support the cancer-fighting abilities associated with consuming broccoli and other members of the crucifer family for more than a decade. Past studies have shown that the […]